◆个人简历
方正锋 长江学者特聘教授，博士生导师，四川农业大学二级教授，四川省学术与技术带头人，中国动物营养分会理事，曾留学美国贝勒医学院。
研究方向：猪的营养
一、 学历和工作简历：
2012.01-至今 四川农业大学 教授、博士生导师
2014.01-2014.12 美国贝勒医学院 访问学者
2008.07-2011.12 四川农业大学 讲师
2005.09-2008.06 华中农业大学 博士
2002.09-2005.06 华中农业大学 硕士
1998.09-2002.06 华中农业大学 本科
二、 教学课程：
承担本科生《动物营养学》、硕士生《动物营养研究进展》、博士生《高级动物营养学》
三、 指导研究生：（整体指导情况介绍）
已培养毕业博/硕士研究生28名，培养在读博士生5名、在读硕士生11名。
四、 当前主要研究工作：(承担的主要科研项目)
主持国家自然科学基金面上项目1项，“十四五”育种攻关项目1项，四川省科研项目2项，主持国际国内横向合作项目多项。
五、代表性科研成果：
学术论文：
[1] Li Zhe;Uffe Krogh;Charlotte Lauridsen;Mette Olaf Nielsen;Zhengfeng Fang and Peter Kappel Theil.Impact of dietary fat levels and fatty acid composition on milk fat synthesis in sows at peak lactation.Journal of Animal Science and Biotechnology,2023,14(1):42(通讯作者).
[2] Sen Lin;Sutian Wang;Peng Wang;Cuiming Tang;Zhenjiang Wang;Lian Chen ;Guoqing Luo;Hong Chen;Yuntao Liu;Bin Feng;De Wu,Douglas G. Burrin and Zhengfeng Fang.Bile acids and their receptors in regulation of gut health and diseases.Progress in Lipid Research,2022,89:101210(通讯作者).
[3] Peng Wang;Qianqian Chen;Peiqiang Yuan;Sen Lin;Hong Chen;Ran Li;Xiaoling Zhang;Yong Zhuo;Jian Li;Lianqiang Che;Bin Feng;Yan Lin;Shengyu Xu;De Wu and Zhengfeng Fang.Gut microbiota involved in desulfation of sulfated progesterone metabolites: A potential regulation pathway of maternal bile acid homeostasis during pregnancy.Frontiers in Microbiology,2022,13:1023623(通讯作者).
[4] Peng Wang;Peiqiang Yuan;Sen Lin;Heju Zhong;Xiaoling Zhang;Yong Zhuo;Jian Li;Lianqiang Che;Bin Feng;Yan Lin;Shengyu Xu;De Wu;Douglas G Burrin and Zhengfeng Fang.International Journal of Molecular Sciences,2022,23(12):6496(通讯作者).
[5] Li Zhe;Rui Zhou;Peter Kappel Theil;Uffe Krogh;Lunxiang Yang;Yong Zhuo;Yan Lin;Shengyu Xu;Xuemei Jiang;Lingjie Huang;Lianqiang Che;Bin Feng;De Wu and Zhengfeng Fang.The Impact of Enhancing Diet Quality or Dietary Supplementation of Flavor and Multi-Enzymes on Primiparous Lactating Sows.Animals,2022,12(12):1493(通讯作者).
[6] Heju Zhong;Peiqiang Yuan;Yunxia Li;Dolores Batonon-Alavo;Caroline Deschamps;Bin Feng;Xiaoling Zhang;Lianqiang Che;Yan Lin;Shengyu Xu;Jian Li;Yong Zhuo;Gang Tian;Jiayong Tang;Xuemei Jiang;Lingjie Huang;Caimei Wu;De Wu and Zhengfeng Fang.Methionine Protects Mammary Cells against Oxidative Stress through Producing S-Adenosylmethionine to Maintain mTORC1 Signaling Activity.Oxidative Medicine and Cellular Longevity,2021,2021:5550196(通讯作者).
[7] Sen Lin;Xiaomin Yang;Yanrong Long;Heju Zhong;Peng Wang,;Peiqiang Yuan;Xiaoling Zhang;Lianqiang Che;Bin Feng;Jian Li;Yong Zhuo;Yan Lin;Shengyu Xu;De Wu and Zhengfeng Fang.Dietary supplementation with Lactobacillus plantarum modified gut microbiota,bile acid profile and glucose homeostasis in weaning piglets.British Journal of Nutrition,2020,124(8):797-808(通讯作者).
[8] Heju Zhong;Yumo Song;Peng Wang;Bin Feng;Xiaoling Zhang;Lianqiang Che;Yan Lin;Shengyu Xu;Jian L;De Wu and Zhengfeng Fang.Mammary protein synthesis upon long-term nutritional restriction was attenuated by oxidative stress induced inhibition of v-ATPase/mTORC1 signaling.American Journal of Physiology-gastrointestinal And Liver Physiology,2019,67(32):8950-8957(通讯作者).
[9] Sen Lin;Xiaomin Yang;Peiqiang Yuan;Jiameng Yang;Peng Wang;Heju Zhong;Xiaoling Zhang;Lianqiang Che;Bin Feng;Jian Li;Yong Zhuo;Yan Lin;Shengyu Xu;De Wu;Douglas G. Burrin and Zhengfeng Fang.Undernutrition Shapes the Gut Microbiota and Bile Acid Profile in Association with Altered Gut-Liver FXR Signaling in Weaning Pigs.Journal of Agricultural and Food Chemistry,2019,67(13):3691-3701(通讯作者).
[10] Peng Wang;Yumo Song;Heju Zhong;Sen Lin;Xiaoling Zhang;Jian Li;Lianqiang Che;Bin Feng ;Yan Lin;Shengyu Xu;Yong Zhuo;De Wu;Douglas G. Burrin and Zhengfeng Fang.Transcriptome Profiling of Placenta through Pregnancy Reveals Dysregulation of Bile Acids Transport and Detoxification Function.International Journal of Molecular Sciences,2019,20(17):4099(通讯作者).
[11] Yalin Zhang; Peng Wang; Sen Lin; Yves Mercier; Huajun Yin; Yumo Song; Xiaoling Zhang; Lianqiang Che; Yan Lin; Shengyu Xu; Bin Feng; De Wu; Zhengfeng Fang. mTORC1 signaling?associated protein synthesis in porcine mammary glands was regulated by the local available methionine depending on methionine sources. Amino Acids, 2017 (10) :1-11. (通讯作者).
[12] Yan Gu; Yumo Song; Huajun Yin; Sen Lin; Xiaoling Zhang; Lianqiang Che; Yan Lin; Shengyu Xu; Bing Feng; De Wu; Zhengfeng Fang. Dietary supplementation with tributyrin prevented weaned pigs from growth retardation and lethal infection via modulation of inflammatory cytokines production, ileal expression and intestinal acetate fermentation. Journal of Animal Science, 2017, 95(1): 226-238. (通讯作者).
[13] Sen Lin; Yalin Zhang; Yanrong Long; Haifeng Wan; Lianqiang Che; Yan Lin; Shengyu Xu; Bin Feng; Jian Li; De Wu; Zhengfeng Fang. Mammary inflammatory gene expression was associated with reproductive stage and regulated by docosahexenoic acid: in vitro and in vivo studies. Lipids in Health and Disease, 2016, 15: 215-222. (通讯作者).
[14] Heju Zhong; Hao Li; Guangmang Liu; Haifeng Wan; Yves Mercier; Xiaoling Zhang; Yan Lin; Lianqiang Che; Shengyu Xu; Li Tang; Gang Tian; Daiwen Chen; De Wu; Zhengfeng Fang. Increased maternal consumption of methionine as its hydroxyl analog promoted neonatal intestinal growth without compromising maternal energy homeostasis. Journal of Animal Science and Biotechnology, 7(46), pp1-14, 2016. (通讯作者).
[15] Yu Wang; Yiwen Kuang; Yalin Zhang; Yumo Song; Xiaoling Zhang; Yan Lin; Lianqiang Che; Shengyu Xu; De Wu; Bai Xue; Zhengfeng Fang. Rearing Conditions Affected Responses of Weaned Pigs to Organic Acids Showing a Positive Effect on Digestibility, Microflora and Immunity, Animal Science Journal, 87 (10), pp1267-1280, 2016. (通讯作者)
[16] Kuang YW, Wang Y, Zhang YL, Song YM, Zhang XL, Lin Y, Che LQ, Xu SY, Wu D, Xue B, Fang ZF*. Effects of dietary combinations of organic acids and medium chain fatty acids as a replacement of zinc oxide on growth, digestibility and immunity of weaned pigs. Animal Feed Science and Technology 2015, 208: 145-157. (通讯作者)
[17] Zhang XL, Li H, Liu GM, Wan HF, Mercier Y, Wu CM, Wu XQ, Che LQ, Lin Y, Xu SY, Tian G, Chen DW, Wu D, Fang ZF*. Differences in plasma metabolomics between sows fed DL-methionine and its hydroxy analogue reveal a strong association of milk composition and neonatal growth with maternal methionine nutrition. British Journal of Nutrition 2015,113: 585-595. (通讯作者)
[18] Li H, Wan HF, Mercier Y, Zhang XL, Wu CM, Wu XQ, Tang L, Che LQ, Lin Y, Xu SY, Tian G, Wu D, Fang ZF*. Changes in plasma amino acid profiles, growth performance and intestinal antioxidant capacity of piglets following increased consumption of methionine as its hydroxy analogue. British Journal of Nutrition 2014,112：855-867. (通讯作者)
[19] Lin S, Hou J, Xiang F，Zhang XL, Che LQ, Lin Y, Xu SY, Zeng QF, Tian G, Yu B, Chen DW, Wu D, Fang ZF*. Mammary inflammation around parturition appeared to be attenuated by consumption of fish oil rich in n-3 polyunsaturated fatty acid. Lipids in Health and Disease 2013,12,190. (通讯作者)
[20] Fang ZF, Yao K, Zhang X, Zhao S, Sun Z, Tian G, Yu B, Lin Y, Zhu B, Jia G, Zhang K, Chen D, Wu D. Nutrition and health relevant regulation of intestinal sulfur amino acid metabolism. Amino Acids. 2010, 39(3): 633–640.
[21] Fang ZF, Luo J, Wei HK, Ma LB, Jiang SW, Peng J. Effects of dl-2-hydroxy-4-methylthiobutyrate on the first-pass intestinal metabolism of dietary methionine and its extra-intestinal availability. British Journal of Nutrition. 2010, 103(5): 643-651.
[22] Fang ZF, Luo H, Wei H, Huang F, Qi Z, Jiang S, Peng J. Methionine metabolism in piglets fed DL-methionine or its hydroxy analogue was affected by distribution of enzymes oxidizing these sources to keto-methionine. Journal of Agricultural and Food Chemistry. 2010, 58(3): 2008-2014.
[23] Fang ZF, Luo J, Qi ZL, Huang FR, Zhao SJ, Liu MY, Jiang SW, Peng J. Effects of 2-hydroxy-4-methylthiobutyrate on portal plasma flow and net portal appearance of amino acids in piglets. Amino acids. 2009, 36(3): 501-509.
[24] Fang ZF, Liu ZL, Qian HY, Qi ZL, Ma LB, Peng J. Effects of enzyme addition on the nutritive value of broiler diets containing hulled or dehulled Chinese double-low rapeseed meals. Journal of Animal Physiology and Animal Nutrition. 2009, 93(4): 467-476.
[25] Fang ZF, Xu HT, Wu D, Zhuo Y, Lin Y, Luo XL. Vitamin A supplements alleviate inflammatory responses in reproductive traits of male mice infected with Pseudorabies virus. International Journal for Vitamin and Nutrition Research. 2010, 80(2): 117-130.
著作：
[1] 猪健康高效饲养环境手册，中国农业出版社，2021，参编
[2] 畜禽环境生物学，科学出版社（北京），2021，参编
[3] 猪肠道健康与营养调控，中国农业出版社，2021，参编
[4] 动物营养学，中国农业出版社，2020，参编
[5] 动物营养学实验指导，中国农业出版社，2017，参编
[6] 雷波芭蕉芋猪《标准化养殖技术手册》，四川农业大学动物营养研究所与雷波县农牧局联合编制，2017，主编
[7] 动物营养与饲料科学研究进展，中国农业出版社，2016，参编
[8] 动物营养与饲料学，中国农业出版社，2015，参编
[9] 猪标准化规模养殖图册，中国农业出版社，2013，参编
[10] 猪抗病营养理论与实践，中国农业大学出版社，2012，参编
专利：
[1] 一种可移动式抓铺装置，实用新型专利，ZL 2022 2 2855216.9，排名第一。
[2] 一种屠宰线末端的滑动式猪胴体冲淋装置，实用新型专利，ZL 2020 2 3259846.7，排名第一。
[3] 一种提高后备母猪育成率的精准化饲喂方法，发明专利，ZL 2020 1 0020165.0，排名第一。
[4] 后备母猪体重预估方法，发明专利，ZL 2019 1 0928447.8，排名第一。
[5] 一种促进母猪胚胎着床的功能性预混剂，发明专利，ZL 2019 1 0928447.8，排名第三。
[6] 一种提高母猪发情的微生态制剂及制备方法和应用，发明专利，ZL 2015 1 0623837.6，排名第三。
[7] 一种快速检测母猪卵母细胞质量的micriRNA分子标记miR-23a及其应用，发明专利，ZL 2015 1 0623895.9，排名第三。
[8] 一种促进母猪卵母细胞减数分裂恢复的组合物及应用，发明专利，ZL 2015 1 0624013.0，排名第三。
[9] 一种促进母猪胚胎肌肉细胞增殖分化的复合添加剂及应用，发明专利，ZL 2015 1 0623803.7，排名第三。
[10] 一种提高母猪发情的微生态制剂及制备方法和应用，发明专利，ZL 2015 1 0623837.6，排名第三。
[11] 一种促进后备母猪发情启动的生物饲料及制备方法和应用，发明专利，ZL 2015 1 0623865.8，排名第三。
[12] 一种猪用纤维源性复合添加剂及其制备方法，发明专利，ZL 2014 1 002285.9，排名第五。
[13] 一种降低雅南猪背膘厚度和提高雅南猪瘦肉沉积率的饲料，发明专利，ZL 2013 1 0286699.8，排名第三。
[14] 一种提高公猪繁殖成绩和繁殖寿命的饲料添加剂，发明专利，ZL 201310060215.8，排名第四。
[15] 一种监测母猪平躺睡眠和站立时间及次数单栏猪圈，实用新型专利，ZL 2013 2 0278093.5，排名第五。
[16] 一种气溶胶紫外光催化空气净化装置，实用新型专利，ZL 2009 2 0127389.0, 排名第三。
[17] 一种仔猪恒温箱，实用新型专利，ZL200920127390.3，排名第三。
获奖：（科技成果奖）
[1] 母猪系统营养技术与应用，国家科技进步二等奖， 2010，排名第六。
[2] 母猪系统营养技术研究与应用，四川省科技进步一等奖，2009，排名第六。
[3] 双低油菜优质饼粕制备饲料技术开发，湖北省科技进步一等奖，2005，排名第十三。
[4] 营养调控母猪胚胎存活与发育的机理及应用，四川省科技进步三等奖， 2014，排名第五。
[5] 营养调控宫内发育迟缓仔猪生长发育关键技术研究与应用大北农科技成果二等奖，2015。
[6] 弱小仔猪生长发育及营养调控关键技术研究与应用， 四川省科技进步二等奖， 2016,排名第七。
[7] 畜牧学科研究生“产学研”融合培养模式构建与实践，国家级教学成果二等奖，2018，排名第十三。
[8] 碳水化合物提高母猪繁殖效率的调控机制研究与应用, 四川省科技进步一等奖，2019，排名第七。
[9] 四川农业大学猪营养与饲料创新团队，中华人民共和国农业农村部，2021，排名第五。
七：奖励和荣誉：（除科技成果奖）
[1] 教育部霍英东青年教师奖（研究类三等奖），2012
[2] 全国优秀博士学位论文提名奖， 2012
[3] 四川省青年科技奖, 2011
[4] 四川农业大学青年教师讲课比赛一等奖，2011
[5] 四川省学术和技术带头人，2018
[6] 长江学者奖励计划特聘教授，2021
八：联系方式：
通讯地址：四川省成都市温江区惠民路211号，邮编：611130
电话号码：138-8243-6056
传真号码：028-8629-0922
电子信箱：375906997@qq.com