朱孝波 更新日期：2024-05-05
朱孝波,男,1986年出生,学硕导师
工作单位 国家重点实验室
电子邮箱 myself19861025@163.com
招生专业 【学硕】:090102作物遗传育种，【专硕】:095131农艺与种业
◆个人简历
朱孝波，男，中共党员，博士，副教授，硕士研究生导师，第十四批四川省学术与技术带头人后备人选。
1986年出生，四川省凉山州越西县人，2006年9月考入四川农业大学生物技术本科专业，2010年保送本校作物遗传育种专业，硕博连读。
2016年博士毕业后进入生物学博士后科研流动站工作，出站后留校工作。
围绕“水稻免疫与细胞死亡”开展基础研究，先后发表论文27篇，主持省部级以上科研项目6项，获四川省科技进步一等奖1项。
◆工作经历
2016.06-2018.04，四川农业大学，生物学博士后科研流动站，讲师；
2018.04-2020.12，四川农业大学，国家重点实验室，讲师；
2021.01至今，四川农业大学，国家重点实验室，副教授。
◆教育经历
2006.09-2010.06，四川农业大学，生物技术专业，本科；
2010.09-2016.06，四川农业大学，作物遗传育种专业，博士（硕博连读）。
◆获奖荣誉
2020年，四川省科技进步一等奖（自然科学类），排名第4。
◆研究领域
以水稻自免疫和细胞死亡突变体为对象，研究植物免疫激活和调控的分子信号。
目前的方向主要有：
1. 胞内蛋白运输过程与水稻免疫和细胞死亡；
2. 糖信号与水稻免疫和细胞死亡；
3. 叶绿体参与的水稻抗病免疫信号；
4. 新免疫和细胞死亡突变体基因的克隆和功能研究。
◆科研项目
1. 2022YFD1401400，水稻抗稻瘟病分子机制及绿色防控策略创新，国家重点研发计划青年科学家项目，60 万元，2022.09.01-2025.12.30，在研；
2. SKL-ZY202215，水稻小肽SPAL6-3对稻瘟病抗性的调控作用，四川农业大学省部共建西南作物基因发掘与利用国家重点实验室生物育种揭榜挂帅自由探索项目，20 万元，2022.09.01-2024.08.31，在研，主持；
3. 32072407，蛋白OsRac1的单泛素化修饰对水稻免疫反应的调控作用，国家自然科学基金（面上），58万元，2021.01-2024.12，在研，主持；
4. 31701779，OsEPSPS3调控水稻稻瘟病抗性的分子机制，国家自然科学基金（青年），28.75万元，2018.01-2020.12，结题，主持；
5. 2019YJ0432，糖代谢关键酶RSMI1调控水稻OsNPR1免疫信号的分子机制，四川省科技厅，10万元，2019.01-2021.01，结题，主持；
6. 2017M612984，VSL2调控水稻细胞死亡和免疫反应的分子机制，中国博士后科学基金，5万元，2017.01-2018.03，结题，主持。
◆发表论文
第一或共同第一作者
(1) Xiaobo Zhu, Sihui Liang, Junjie Yin, Can Yuan, Jing Wang, Weitao Li, Min He, Jichun Wang, Weilan Chen, Bingtian Ma, Yuping Wang, Peng Qin, Shigui Li, Xuewei Chen*, The DnaJ OsDjA7/8 is essential for chloroplast development in rice (Oryza sativa). Gene, 2015. 574(1): p. 11-19.
(2) Junjie Yin#, Xiaobo Zhu#, Can Yuan#, Jing Wang#, Weitao Li, Yuping Wang, Min He, Qinshu Cheng, Bangquan Ye, Weilan Chen, Qianyan Linghu, Jichun Wang, Bingtian Ma, Peng Qin, Shigui Li, Xuewei Chen*, Characterization and Fine Mapping of a Novel Vegetative Senescence Lethal Mutant Locus in Rice. Journal of Genetics and Genomics, 2015. 42(9): p. 511-514.
(3) Xiaobo Zhu#, Junjie Yin#, Sihui Liang, Ruihong Liang, Xiaogang Zhou, Zhixiong Chen, Wen Zhao, Jing Wang, Weitao Li, Min He, Can Yuan, Koji Miyamoto, Bingtian Ma, Jichun Wang, Peng Qin, Weilan Chen, Yuping Wang, Wenming Wang, Xianjun Wu, Hisakazu Yamane, Lihuang Zhu, Shigui Li,Xuewei Chen, The Multivesicular Bodies (MVBs)-Localized AAA ATPase LRD6-6 Inhibits Immunity and Cell Death Likely through Regulating MVBs-Mediated Vesicular Trafficking in Rice. PLoS Genetics, 2016. 12(9): p. e1006311.
(4) Xiaobo Zhu#, Mu Ze#, Junjie Yin, Mawsheng Chern, Mingrui Wang, Xiang Zhang, Rui Deng, Yongzhen Li, Haicheng Liao, Long Wang, Bin Tu, Li Song, Min He, Shigui Li, Wen-Ming Wang, Xuewei Chen, Jing Wang, Weitao Li*, A phosphofructokinase B-type carbohydrate kinase family protein, PFKB1, is essential for chloroplast development at early seedling stage in rice. Plant Science, 2020. 290: p. 110295.
(5) Zhu Xiaobo, Ze Mu, Chern Mawsheng, Chen Xuewei, Wang Jing*, Deciphering Rice Lesion Mimic Mutants to Understand Molecular Network Governing Plant Immunity and Growth. Rice Science, 2020. 27(4): p. 278-288.
(6) Ziwei Zhu#, Junjie Yin#, Mawsheng Chern#, Xiaobo Zhu#, Chao Yang, Kaiwei He, Yuchen Liu, Min He, Jing Wang, Li Song, Long Wang, Yingjie Wei, Jichun Wang, Jiali Liu, Hai Qing, Yu Bi, Mingwu Li, Kun Hu, Tuo Qi, Qingqing Hou, Xuewei Chen, Weitao Li*, New insights into bsr-d1-mediated broad-spectrum resistance to rice blast. Molecular Plant Pathology, 2020. 21(7): p. 951-960.
(7) 朱孝波, 李伟滔, 贺闽, 王静, 于振良, 陈学伟, 作物广谱抗病研究现状与关键科学问题. 中国科学基, 2020. 04: p. 401-410.
(8) Yan Zhao#, Xiaobo Zhu#, Xuewei Chen*, Jian-Min Zhou*, From plant immunity to crop disease resistance. Journal of Genetics and Genomics, 2022. 49(8): 693-703.
(9) Xiaobo Zhu, Xuewei Chen, A "protector" model for membrane trafficking-regulated and NLR-mediated plant immunity, Molecular Plant, 2023. 16(2),303-305.

其他作者
(1) 周勇, 朱孝波, 袁华, 郑英, 钦鹏, 魏应海, 王玉平, 黄世君,李仕贵, 水稻单片段代换系芽期和苗期耐冷性分析及耐冷性QTL鉴定. 中国水稻科学, 2013. 27(4): p. 381-388.
(2) Xiaogang Zhou#, Jing Wang#, Chunfang Peng, Xiaobo Zhu, Junjie Yin, Weitao Li, Min He, Jichun Wang, Mawsheng Chern, Can Yuan, Wenguan Wu, Weiwei Ma, Peng Qin, Bintian Ma, Xianjun Wu, Shigui Li, Pamela Ronald, Xuewei Chen*, Four receptor-like cytoplasmic kinases regulate development and immunity in rice. Plant Cell Environ, 2016. 39(6): p. 1381-1392.
(3) Weitao Li, Ziwei Zhu, Mawsheng Chern, Junjie Yin, Chao Yang, Li Ran, Mengping Cheng, Min He, Kang Wang, Xiaogang Zhou, Xiaobo Zhu, Zhixiong Chen, Jichun Wang, Wen Zhao, Bingtian Ma, Peng Qin, Weilan Chen, Yuping Wang, Xuewei Chen, A Natural Allele of a Transcription Factor in Rice Confers Broad-Spectrum Blast Resistance. Cell, 2017. 170: p. 114-126.e15.
(4) Jing Wang, Lian Zhou, Hui Shi, Mawsheng Chern, Hong Yu, Hong Yi, Min He, Junjie Yin, Xiaobo Zhu, Yan Li, Weitao Li, Jiali Liu, Jichun Wang, Xiaoqiong Chen, Hai Qing, Yuping Wang, Guifu Liu, Wenming Wang, Ping Li, Xianjun Wu, Lihuang Zhu, Jian-Min Zhou, Pamela C. Ronald, Shigui Li, Jiayang Li, Xuewei Chen, A single transcription factor promotes both yield and immunity in rice. Science, 2018. 361(6406): p. 1026-1028.
(5) Xiaogang Zhou#, Haicheng Liao#, Mawsheng Chern#, Junjie Yin#, Yufei Chen, Jianping Wang, Xiaobo Zhu, Zhixiong Chen, Can Yuan, Wen Zhao, Weitao Li, Min He, Bingtian Ma, Jichun Wang, Peng Qin, Weilan Chen, Yuping Wang, Jiali Liu, Xuewei Chen*, Loss of function of a rice TPR-domain RNA-binding protein confers broad-spectrum disease resistance. Proceedings of the National Academy of Sciences, 2018. 115: p. 201705927.
(6) Min He, Youpin Xu, Jinhua Chen, Yuan Luo, Yang Lv, Jia Su, Michael J. Kershaw, Weitao Li, Jing Wang, Junjie Yin, Xiaobo Zhu, Xiaohong Liu, Mawsheng Chern, Bingtian Ma, Jichun Wang, Peng Qin, Weilan Chen, Yuping Wang, Wenming Wang, Zhenglong Ren, Xianjun Wu, Ping Li, Shigui Li, Youliang Peng, Fucheng Lin, Nicholas J. Talbot,Xuewei Chen, MoSnt2-dependent deacetylation of histone H3 mediates MoTor-dependent autophagy and plant infection by the rice blast fungus Magnaporthe oryzae. Autophagy, 2018. 14(9): p. 1543-1561.
(7) Zhixiong Chen#, Wen Zhao#, Xiaobo Zhu, Chengdong Zou, Junjie Yin, Mawsheng Chern, Xiaogang Zhou, Heng Ying, Xin Jiang, Yongzhen Li, Haicheng Liao, Mengping Cheng, Weitao Li, Min He, Jing Wang, Jichun Wang, Bingtian Ma, Jirui Wang, Shigui Li, Lihuang Zhu, Xuewei Chen*, Identification and characterization of rice blast resistance gene Pid4 by a combination of transcriptomic profiling and genome analysis. Journal of Genetics and Genomics, 2018. 45(12): p. 663-672.
(8) 李伟滔, 朱紫薇, 尹俊杰, 贺闽, 王静, 朱孝波, 陈学伟, 水稻“抗癌”新因子bsr-d1. 自然杂志, 2018. 40(2): p. 131-135.
(9) Min He#, Jia Su#, Youpin Xu#, Jinhua Chen#, Mawsheng Chern#, Mingliang Lei, Tuo Qi, Zongkuan Wang, Lauren S. Ryder, Bozeng Tang, Míriam Osés-Ruiz, Keke Zhu, Yuyan Cao, Xia Yan, Iris Eisermann, Yuan Luo, Weitao Li, Jing Wang, Junjie Yin, Sin Man Lam, Guoxiong Peng, Xiaofang Sun, Xiaobo Zhu, Bingtian Ma, Jichun Wang, Jiali Liu, Hai Qing, Li Song, Long Wang, Qingqing Hou, Peng Qin, Yan Li, Jing Fan, Deqiang Li, Yuping Wang, Xiue Wang, Ling Jiang, Guanghou Shui, Yuxian Xia, Guoshu Gong, Fu Huang, Wenming Wang, Xianjun Wu, Ping Li, Lihuang Zhu, Shigui Li, Nicholas J. Talbot, Xuewei Chen*, Discovery of broad-spectrum fungicides that block septin-dependent infection processes of pathogenic fungi. Nature Microbiology, 2020. 5: p.1565–1575.
(10) Weitao Li, Kang Wang, Mawsheng Chern, Yuchen Liu, Ziwei Zhu, Jiang Liu, Xiaobo Zhu, Junjie Yin, Li Ran, Jun Xiong, Kaiwei He, Liting Xu, Min He, Jing Wang, Jiali Liu, Yu Bi, Hai Qing, Mingwu Li, Kun Hu, Li Song, Long Wang, Tuo Qi, Qingqing Hou, Weilan Chen, Yan Li, Wenming Wang, Xuewei Chen, Sclerenchyma cell thickening through enhanced lignification induced by OsMYB30 prevents fungal penetration of rice leaves. New Phytologist, 2020. 226(6): p. 1850-1863.
(11) Lianan Guo, Weilan Chen, Lei Tao, Binhua Hu, Guoli Qu, Bin Tu, Hua Yuan, Bingtian Ma, Yuping Wang, Xiaobo Zhu, Peng Qin, Shigui Li*, GWC1 is essential for high grain quality in rice. Plant Science, 2020. 296: p. 110497.
(12) Bin Tu, Tao Zhang, Yuping Wang, Li Hu, Jin Li, Ling Zheng, Yi Zhou, Jialian Li, Fengyin Xue, Xiaobo Zhu, Hua Yuan, Weilan Chen, Peng Qin, Bingtian Ma, Shigui Li*, Membrane-associated xylanase-like protein OsXYN1 is required for normal cell wall deposition and plant development in rice. Journal of Experimental Botany, 2020. 71(16): p. 4797-4811.
(13) 贺闽, 尹俊杰, 冯志明, 朱孝波, 赵剑华, 左示敏, 陈学伟, 水稻稻瘟病和纹枯病抗性鉴定方法. 植物学报, 2020. 55(5): p. 577-587.
(14) Li Hu, Bin Tu, Wen Yang, Hua Yuan, Jialian Li, Lianan Guo, Ling Zheng, Weilan Chen, Xiaobo Zhu, Yuping Wang, Peng Qin, Bingtian Ma, Shigui Li*, Mitochondria-Associated Pyruvate Kinase Complexes Regulate Grain Filling in Rice. Plant Physiology, 2020. 183(3): p. 1073.
(15) Li Hu, Weilan Chen, Wen Yang, Xiaoling Li, Cheng Zhang, Xiaoyu Zhang, Ling Zheng, Xiaobo Zhu, Junjie Yin, Peng Qin, Yuping Wang, Bingtian Ma, Shigui Li, Hua Yuan, Bin Tu, OsSPL9 Regulates Grain Number and Grain Yield in Rice. Frontiers in Plant Science, 2021. 12(979).
(16) Junjie Yin#, Lijuan Zou#, Xiaobo Zhu, Yuyan Cao, Min He*, Xuewei Chen*, Fighting the enemy: How rice survives the blast pathogen’s attack. The Crop Journal, 2021. 9(3): p. 543-552.
(17) Bin Tu, Zhang Tao, Shiguang Wang, Lei Zhou, Ling Zheng, Chun Zhang, Xinzi Li, Xiaoyu Zhang, Junjie Yin, Xiaobo Zhu, Hua Yuan, Ting Li, Weilan Chen, Peng Qin, Bingtian Ma, Yuping Wang,Shigui Li, Loss of Gn1a/OsCKX2 confers heavy-panicle rice with excellent lodging resistance. Journal of Integrative Plant Biology, 2022. 64(1): 23-38.
(18) Hua Yuan, Peng Gao, Xiaoling Hu, Min Yuan, Zhengyan Xu, Mengya Jin, Wencheng Song, Shijie Zhan, Xiaobo Zhu, Bin Tu, Ting Li, Yuping Wang, Bingtian Ma, Peng Qin, Weilan Chen,Shigui Li, Fine mapping and candidate gene analysis of qGSN5, a novel quantitative trait locus coordinating grain size and grain number in rice. Theoretical and Applied Genetics, 2022. 135(1): 51-64.
◆指导学生
指导毕业硕士研究生2名；
在读硕士研究生6名。