◆个人简历
姜维丹,博士,教授(二级),博士研究生导师,四川农业大学水产学院水产动物营养与饲料研究室(系)主任,四川省学术和技术带头人、四川省“天府青城计划”科技创新领军人才、四川省畜牧兽医学会动物营养学分会理事,四川省杰出青年科学基金、2020“颐和”青年创新奖获得者,农业部科技创新团队、四川省青年科技创新团队和四川省高校科技创新团队的核心成员,曾留学加拿大英属哥伦比亚大学。主要从事淡水鱼健康营养调控理论及其技术的研究工作;主持和(或)主研国家自然科学基金、省部级和横向项目近20项。获国家科技进步二等奖2项(排名分别为第6、第9)、四川省科技进步一等奖1项(排名第4);获授权国家发明专利21件;参编著作1部;以第一作者和(或)通讯作者发表SCI收录论文近80篇,入选全球前2%顶尖科学家终身科学影响力榜单。
◆科研项目
1.国家自然科学基金面上项目,肌醇通过Lox/细胞亚群FN/跨膜信号调控鱼类肌纤维肥大的机制研究,2026.01-2029.12;
2.国家自然科学基金面上项目,MLKL信号途径在调控鱼类鳃细胞坏死致烂鳃中的作用和机制研究,2020.01-2023.12;
3.国家自然科学基金面上项目,大豆球蛋白调控鱼肠ROS产生的NOX信号通路作用机制研究,2017.01-2020.12;
4.国家自然科学基金青年项目,肌醇促进鱼肠细胞增殖与信号分子E2F4的关系研究,2014.01-2016.12;
5.四川省科技厅杰出青年科技人才项目,肌醇促进鱼类肌肉生长与成肌细胞融合的关系及机制研究,2020.01-2022.12;
6.四川省重点研发计划项目,缓解鱼类低氧应激的营养调控技术研究,2024.07-2026.06。
◆发表论文
代表论文如下:
1.Mitigation of the toxic effects of nitrite: Role and mechanism of isoleucine in mitigating mitochondrial DNA leakage-induced inflammation in grass carp (Ctenopharyngodon idella) under nitrite exposure, Journal of Hazardous Materials, 2025, 491: 138016.(通讯作者,SCI,中科院一区、TOP期刊,IF=12.2)
2.Hypoxia leads to gill endoplasmic reticulum stress and disruption of mitochondrial homeostasis in grass carp (Ctenopharyngodon idella): mitigation effect of thiamine, Journal of Hazardous Materials, 2024, 469: 134005.(通讯作者,SCI,中科院一区、TOP期刊,IF=13.6)
3.Regulation of muscle springiness and hardness: the role of myo-inositol in enhancing fish flesh texture, Food Chemistry: X, 2025, 29: 102788.(通讯作者,SCI,中科院一区、TOP期刊,IF=8.2)
4.Dietary vitamin C improves muscle hardness and springiness associated with collagen and elastin synthesis in grass carp (Ctenopharyngodon idella), Food Research International, 2025, 213: 116591.(通讯作者,SCI,中科院一区、TOP期刊,IF=8.0)
5.Multiple ways to promote adult grass carp (Ctenopharyngodon idella) muscle hypertrophy: Application of dietary myo-inositol, Animal Nutrition, 2025, 21: 326-340. (通讯作者,SCI,中科院一区、TOP期刊,IF=7.5)
6.Glutathione mitigates hypoxia-induced gill damage in juvenile grass carp (Ctenopharyngodon idellus) by alleviating endoplasmic reticulum stress and autophagy, Journal of Animal Science and Biotechnology, 2025, 16: 144. (通讯作者,SCI,中科院一区、TOP期刊,IF=6.5)
7.Exploring new benefits of vitamin A: alleviating hypoxia-induced mitochondrial stress and mitophagy in the gills of adult grass carp (Ctenopharyngodon idellus), Journal of Animal Science and Biotechnology, 2025, 16: 172. (通讯作者,SCI,中科院一区、TOP期刊,IF=6.5)
8.Alpha-linolenic acid/linoleic acid ratio can effectively promote muscle growth and protein deposition in grass carp (Ctenopharyngodon idella), Food Bioscience, 2024, 61: 104968. (通讯作者,SCI,中科院一区、TOP期刊,IF=4.8)
9.A new insight on copper: Promotion of collagen synthesis and myofiber growth and development in juvenile grass carp (Ctenopharyngodon idella), Animal Nutrition, 2023, 15: 22-33.(通讯作者,SCI,中科院一区、TOP期刊,IF=7.5)
10.Promotion of fatty acid metabolism and glucose metabolism in the muscle of sub-adult grass carp (Ctenopharyngodon idella): The role of alpha-linoleic acid/linoleic acid (ALA/LNA) ratios, Food Chemistry: X, 2023, 19: 100752.(通讯作者,SCI,中科院一区、TOP期刊,IF=8.2)